As of 2019, there are five regional NWFZ in the world: the Treaty of Tlatelolco, Treaty of Rarotonga, Treaty of Bangkok, Treaty of Pelindaba, and finally the Treaty on a Nuclear-Weapon-Free Zone in Central Asia (CANWFZ). The CANWFZ is a legally binding obligation not to manufacture, acquire, test, or possess nuclear weapons in or by the Republic of Kazakhstan, the Republic of Kyrgyzstan,  the Republic of Tajikistan,  the Republic of Turkmenistan, and the Republic of Uzbekistan. This treaty was signed at the Semipalatinsk Test Site in Kazakhstan on September 8, 2006 and is a clear victory for nonproliferation and disarmament measures. However, this treaty almost did not come to fruition due to power plays but the United States and the Russian Federation.

It seems that a necessary condition for convening the Helsinki should be its depoliticization – that is, turning it into an objective, technical discussion, a discussion of concrete steps toward reducing the risk of WMD proliferation and developing of the beginnings of arms control for the region.